Beyond surgical radicality in intramedullary spinal cord metastases: neurological function and systemic disease burden drive patient outcomes
Surgical management of ISCM can be performed safely with minimal neurological morbidity, achieving symptom stabilization or improvement. Although GTR was associated with favorable short-term survival, systemic disease burden and postoperative neurological function are stronger prognostic factors. Therefore, surgical decisions should prioritize functional preservation and patient selection based on disease extent and overall health.
Authors
- Sandro M. Krieg (ORCID: https://orcid.org/0000-0003-4050-1531)
- Meltem Ivren
- Sebastian Ille (ORCID: https://orcid.org/0000-0003-2065-6464)
- Deniz Yalman (ORCID: https://orcid.org/0000-0002-4010-8353)
- Pavlina Lenga (ORCID: https://orcid.org/0000-0003-3842-0783)
- Basem Ishak (ORCID: https://orcid.org/0000-0002-6414-4295)
Institutions
- Heidelberg University (DE)
- Helios Dr. Horst Schmidt Kliniken Wiesbaden (DE)
- Deutsche Klinik für Diagnostik (DE)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1007/s11060-025-05119-5
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00