Early detection of opioid-induced hyperalgesia after an ICU stay using quantified sensory testing: An observational cohort case–control study
Our findings underscore the importance of QST in early OIH detection, identifying thermal tolerance thresholds and thermal/mechanical temporal summation tests as sensitive indicators. Subclinical hyperalgesia in ICU patients on opioids heightens susceptibility to chronic pain development, emphasizing the need for vigilant opioid monitoring and adjustment in ICU care.
Authors
- É. Serra (ORCID: https://orcid.org/0000-0002-1921-0097)
- Paul Tarpin (ORCID: https://orcid.org/0009-0008-1614-7759)
- Yazine Mahjoub (ORCID: https://orcid.org/0000-0002-5867-146X)
- V. Martinez (ORCID: https://orcid.org/0000-0003-0552-3583)
Institutions
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Raymond-Poincaré (FR)
- Université de Picardie Jules Verne (FR)
Publication Details
- Journal
- British Journal of Pain
- Published
- 2025-06-30
- DOI
- https://doi.org/10.1177/20494637251356830
- Citations
- 1
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Fondation de France