Interim Analysis of 48-week Tenofovir Amibufenamide Treatment in Chronic Hepatitis B Patients with Normal Alanine Aminotransferase Levels: The PROMOTE Study

TMF treatment demonstrates significant efficacy in chronic HBV-infected patients with normal ALT levels and shows a favorable safety profile regarding bone, renal, and lipid parameters. The PROMOTE study is ongoing, and further results at 96 and 144 weeks are expected to provide additional insights.

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Publication Details

Journal
Journal of Clinical and Translational Hepatology
Published
2025-06-30
DOI
https://doi.org/10.14218/jcth.2025.00162
Citations
1
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
1.35
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article

Interim Analysis of 48-week Tenofovir Amibufenamide Treatment in Chronic Hepatitis B Patients with Normal Alanine Aminotransferase Levels: The PROMOTE Study

Jiaojian Lv, Lin Tan, Honglian Gui, Qian Feng et al.
1 citations
Journal of Clinical and Translational Hepatology
Hepatitis B Virus Studies
1.35
article

Interim Analysis of 48-week Tenofovir Amibufenamide Treatment in Chronic Hepatitis B Patients with Normal Alanine Aminotransferase Levels: The PROMOTE Study

Jiaojian Lv, Lin Tan, Honglian Gui, Qian Feng, Lihong Qu, Yan Huo, Xiaoping Wu, Sujun Zheng, Qing Xie, Zhizhen Hu, Jun Li, Yuanwang Qiu, Yan Shen, Yongfang Jiang, Yunzhen Shi, FuLi Nie, Piao Hu
article en
1 citations

Abstract

TMF treatment demonstrates significant efficacy in chronic HBV-infected patients with normal ALT levels and shows a favorable safety profile regarding bone, renal, and lipid parameters. The PROMOTE study is ongoing, and further results at 96 and 144 weeks are expected to provide additional insights.

Journal of Clinical and Translational HepatologyVol. 000(000)
Central South University (CN), Nanchang University (CN), Shanghai Jiao Tong University (CN), Capital Medical University (CN), Wenzhou Medical University (CN), Ruijin Hospital (CN), Soochow University (CN), Hansoh Pharma (China) (CN), Lishui City People's Hospital (CN), Shanghai East Hospital (CN), Beijing YouAn Hospital (CN), Second Xiangya Hospital of Central South University (CN), Dongyang People's Hospital (CN), The First People's Hospital of Xiaoshan District, Hangzhou (CN), Wuxi People's Hospital (CN), Jiangsu Provincial Hospital of Traditional Chinese Medicine (CN), First Affiliated Hospital of Nanchang University (CN), The Fifth People’s Hospital of Suzhou (CN), Fuyang Second People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 18%
Hepatitis B Virus Studies
1.35
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