Innovations and Mechanisms in Liposomal Drug Delivery: A Comprehensive Introduction

Liposomal drug delivery systems are one of the most promising innovations to revolutionize this pharmaceutical industry. It incorporates drugs with hydrophilic as well as hydrophobic properties into a biocompatible lipid bilayer. In this review, general properties of liposomes will be discussed, including composition and mechanisms involved in the augmentation of drug solubility, stability, and targeted delivery. It referred to the development of liposomal formulations and important milestones, such as the FDA approval of Doxil, as the turning points in the clinical application of liposomes. It has been used in the therapeutic field of oncology where the systemic toxicity reduces simultaneously while making the therapy more effective. Also emphasized in this paper are the advantages of liposomal systems, sustained release profiles, and combination therapies that can help against the problem of drug resistance. A further review of the current clinical applications of liposomes is advanced in order to show successful products which have, indeed, impacted the treatment of a patient. There's a good scope for the integration of liposomal technology with novel therapeutic strategies and it's in this direction that the mandate of treating more effectively and personalizing treatment may be considered. The review focuses on the critical role of liposomal drug delivery systems in modern medicine, underlining their potential to revolutionize therapeutic approaches and patient outcomes.

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Publication Details

Journal
International Journal of Advanced Nano Computing and Analytics
Published
2025-06-30
DOI
https://doi.org/10.61797/ijanca.v4i1.418
Citations
1
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
Field-Weighted Citation Impact
0.60
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article

Innovations and Mechanisms in Liposomal Drug Delivery: A Comprehensive Introduction

Ashutosh Sengar
1 citations
International Journal of Advanced Nano Computing and Analytics
Nanoparticle-Based Drug Delivery
0.60
article

Innovations and Mechanisms in Liposomal Drug Delivery: A Comprehensive Introduction

Ashutosh Sengar
article en
1 citations

Abstract

Liposomal drug delivery systems are one of the most promising innovations to revolutionize this pharmaceutical industry. It incorporates drugs with hydrophilic as well as hydrophobic properties into a biocompatible lipid bilayer. In this review, general properties of liposomes will be discussed, including composition and mechanisms involved in the augmentation of drug solubility, stability, and targeted delivery. It referred to the development of liposomal formulations and important milestones, such as the FDA approval of Doxil, as the turning points in the clinical application of liposomes. It has been used in the therapeutic field of oncology where the systemic toxicity reduces simultaneously while making the therapy more effective. Also emphasized in this paper are the advantages of liposomal systems, sustained release profiles, and combination therapies that can help against the problem of drug resistance. A further review of the current clinical applications of liposomes is advanced in order to show successful products which have, indeed, impacted the treatment of a patient. There's a good scope for the integration of liposomal technology with novel therapeutic strategies and it's in this direction that the mandate of treating more effectively and personalizing treatment may be considered. The review focuses on the critical role of liposomal drug delivery systems in modern medicine, underlining their potential to revolutionize therapeutic approaches and patient outcomes.

International Journal of Advanced Nano Computing and AnalyticsVol. 4(1)
Seva Mandir (IN)
Openalex Percentile: Top 32%
Nanoparticle-Based Drug Delivery
0.60
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