Identification of Androgen Receptor as a Molecular Docking Target for Survival and Response to Metformin‐Induced Ferroptosis in Liver Cancer

This research has developed a prognostic model for ferroptosis suppressor genes through the analysis of the ferroptosis process induced by metformin in liver cancer. It also screened and validated AR as a potential molecular docking target for metformin.

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Publication Details

Journal
Cancer Reports
Published
2025-06-30
DOI
https://doi.org/10.1002/cnr2.70245
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of Androgen Receptor as a Molecular Docking Target for Survival and Response to Metformin‐Induced Ferroptosis in Liver Cancer

Jinghui Zhang, Zili Dai, Yuzi Xu, Mengna Zhang et al.
Cancer Reports
Ferroptosis and cancer prognosis
article

Identification of Androgen Receptor as a Molecular Docking Target for Survival and Response to Metformin‐Induced Ferroptosis in Liver Cancer

Jinghui Zhang, Zili Dai, Yuzi Xu, Mengna Zhang, Zehao Yu, Bin Zhang, Jiyun Zhu, Siming Zheng
article en

Abstract

This research has developed a prognostic model for ferroptosis suppressor genes through the analysis of the ferroptosis process induced by metformin in liver cancer. It also screened and validated AR as a potential molecular docking target for metformin.

Cancer ReportsVol. 8(7)
Ningbo University (CN), Zhejiang University (CN)
Strong, Ningbo University
Good health and well-being
Openalex Percentile: Top 75%
Ferroptosis and cancer prognosis
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