Development of a predictive model for progression to castration-resistant prostate cancer in patients with high bone tumor burden
Perineural invasion, Gleason score ≥8, and elevated ALP and LDH are closely associated with progression from HBTB-PCa to CRPC. The constructed Nomogram (internal AUC=0.845; external AUC=0.746) offers a practical tool for individualized risk assessment and guiding treatment planning in clinical settings.
Authors
- Wei‐Chih Chen (ORCID: https://orcid.org/0000-0003-4172-5529)
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- American Journal of Cancer Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62347/ytso4314
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province