BIOMEDICAL IMAGING AND STRUCTURAL ASSESSMENT OF BONE TISSUE DURING OSSEOINTEGRATION

This paper presents approaches to assessing bone tissue changes before and after osseointegrative prosthetics using modern information and measurement technologies. Particular attention is paid to a comprehensive analysis of the state of bone structures at different stages of osseointegration, which allows for a deeper understanding of the processes of tissue remodelling under the influence of implantation. One of the key research tools is the use of high-resolution computed tomography data. Based on the obtained tomographic slices, three-dimensional (3D) models of bone structures are built using specialised software. These models provide a detailed visualisation of the anatomical features, spatial location of the implant and surrounding tissues, and allow for the analysis of morphological changes resulting from the osseointegration process. In addition to the morphological assessment, mechanical testing of the bone tissue is carried out as part of the work. Loading methods are used to determine physical and mechanical characteristics such as strength, stiffness and elastic properties of the bone in the area of contact with the implant. This allows not only to detect structural changes but also to assess their impact on the functional capacity of the musculoskeletal system after prosthetics. The results are combined into a single data set for comprehensive analysis. This approach allows us to objectively assess the effectiveness of the osseointegration process, identify potential risk areas for implant stability, and formulate recommendations for individualising prosthetic planning for each patient. An important feature of the applied methodology is the possibility of early detection of pathological changes or unsatisfactory implant integration by monitoring the dynamics of morphometric and mechanical parameters in the postoperative period. This opens up prospects for improving the overall success of osseointegrative prosthetics and reducing the number of complications associated with implant instability or rejection. Thus, the developed approach demonstrates high informative value and practical significance, providing a multilevel assessment of bone tissue condition, which is extremely important for ensuring long-term stability and functionality of prostheses in clinical practice.