A Longitudinal Assessment of Anterior Cingulate Cortex Gamma-aminobutyric Acid in Antipsychotic Medication-naïve First Episode Psychosis Patients
Our findings suggest that GABA dysfunction in the ACC may be an important feature of the core pathophysiology of psychosis. This dysfunction does not appear to be attenuated by conventional antipsychotic treatment, though baseline levels may be indicative of clinical prognosis in FEP.
Authors
- Genelle D. Samson (ORCID: https://orcid.org/0000-0001-5672-847X)
- Seyedeh Nasim Adnani
- Adrienne C. Lahti (ORCID: https://orcid.org/0000-0002-5565-7662)
- William P. Armstrong
- Eric Nelson (ORCID: https://orcid.org/0000-0002-4084-8570)
- Jose O. Maximo (ORCID: https://orcid.org/0000-0002-7204-8623)
- Branden Benningfield
- Nina V. Kraguljac (ORCID: https://orcid.org/0000-0003-2567-4098)
- Adil Bashir (ORCID: https://orcid.org/0000-0003-2030-9294)
Institutions
- University of Alabama at Birmingham (US)
- Auburn University (US)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1093/schbul/sbaf079
- Citations
- 1
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- National Institutes of Health
- National Institute of Mental Health