A Case Report of Metastatic Primary Thyroid Sarcoma Evaluated by 18F-FDG PET/CT

Among the thyroid malignancies, primary thyroid sarcomas are very rare, comprising < 1% of all thyroid malignancies. Sarcoma, in particular spindle cell sarcomas of the thyroid gland, is very rare and aggressive which carries poor prognosis. Very little has been published regarding imaging findings and metastatic patterns of this rare entity. We report a case of metastatic spindle cell sarcoma of the thyroid presenting with hoarseness of voice and anterior neck swelling. Subsequent fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) imaging demonstrated a fluorine-18-FDG avid mass lesion in the left lobe of the thyroid, along with FDG avid cervical lymph nodes and multiple FDG avid nodules of varying sizes in the bilateral lung fields. <sup>18</sup>F-FDG PET/CT proved invaluable in accurately staging this rare case of metastatic high-grade sarcoma originating from the thyroid.

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Publication Details

Journal
Indian Journal of Nuclear Medicine
Published
2025-03-01
DOI
https://doi.org/10.4103/ijnm.ijnm_147_24
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
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article

A Case Report of Metastatic Primary Thyroid Sarcoma Evaluated by 18F-FDG PET/CT

Vidya Satish, Kritika Dewan, Abhishek Kumar, Archana Yadav
Indian Journal of Nuclear Medicine
Thyroid Cancer Diagnosis and Treatment
article

A Case Report of Metastatic Primary Thyroid Sarcoma Evaluated by 18F-FDG PET/CT

Vidya Satish, Kritika Dewan, Abhishek Kumar, Archana Yadav
article en

Abstract

Among the thyroid malignancies, primary thyroid sarcomas are very rare, comprising < 1% of all thyroid malignancies. Sarcoma, in particular spindle cell sarcomas of the thyroid gland, is very rare and aggressive which carries poor prognosis. Very little has been published regarding imaging findings and metastatic patterns of this rare entity. We report a case of metastatic spindle cell sarcoma of the thyroid presenting with hoarseness of voice and anterior neck swelling. Subsequent fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) imaging demonstrated a fluorine-18-FDG avid mass lesion in the left lobe of the thyroid, along with FDG avid cervical lymph nodes and multiple FDG avid nodules of varying sizes in the bilateral lung fields. <sup>18</sup>F-FDG PET/CT proved invaluable in accurately staging this rare case of metastatic high-grade sarcoma originating from the thyroid.

Indian Journal of Nuclear MedicineVol. 40(2)
Army Hospital Research and Referral (IN)
No poverty
Openalex Percentile: Top 77%
Thyroid Cancer Diagnosis and Treatment
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