Thyroid Scan Conundrum in a Rare Case of McCune–Albright Syndrome

McCune-Albright syndrome is a rare and challenging disorder characterized by a triad of cutaneous, bone and multiple endocrine abnormalities. We present the case of a 15-year-old female with varied symptoms including precocious puberty, prolactinoma, polyostotic fibrous dysplasia, and hyperthyroidism. On examination, she had a palpable nodule in the right lobe of the thyroid with an atrophic left lobe on ultrasonography. Thyroid scan in this patient posed a diagnostic challenge which was resolved with additional single-photon emission computed tomography/computed tomography (SPECT/CT). On SPECT/CT, she was diagnosed with autonomously functioning thyroid nodule and treated with 15 mCi of <sup>131</sup>I.

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Publication Details

Journal
Indian Journal of Nuclear Medicine
Published
2025-03-01
DOI
https://doi.org/10.4103/ijnm.ijnm_144_23
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
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article

Thyroid Scan Conundrum in a Rare Case of McCune–Albright Syndrome

Nikhil Tandon, Yogita Khandelwal, Manasvini Bhatt, Chandrasekhar Bal et al.
Indian Journal of Nuclear Medicine
Bone Tumor Diagnosis and Treatments
article

Thyroid Scan Conundrum in a Rare Case of McCune–Albright Syndrome

Nikhil Tandon, Yogita Khandelwal, Manasvini Bhatt, Chandrasekhar Bal, G B Priyanka, Bela Jain
article en

Abstract

McCune-Albright syndrome is a rare and challenging disorder characterized by a triad of cutaneous, bone and multiple endocrine abnormalities. We present the case of a 15-year-old female with varied symptoms including precocious puberty, prolactinoma, polyostotic fibrous dysplasia, and hyperthyroidism. On examination, she had a palpable nodule in the right lobe of the thyroid with an atrophic left lobe on ultrasonography. Thyroid scan in this patient posed a diagnostic challenge which was resolved with additional single-photon emission computed tomography/computed tomography (SPECT/CT). On SPECT/CT, she was diagnosed with autonomously functioning thyroid nodule and treated with 15 mCi of <sup>131</sup>I.

Indian Journal of Nuclear MedicineVol. 40(2)
All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 75%
Bone Tumor Diagnosis and Treatments
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