68Ga-PSMA PET/CT in a case of recurrent Glioblastoma

Glioblastoma multiforme (GBM) is a high-grade brain tumor with a high recurrence rate. We present the case of a 57-year-old man with left frontal lobe GBM who was operated on and received radiation therapy in June 2023 and was referred for <sup>68</sup>Ga-PSMA 11 PET/CT with a clinical suspicion of recurrence. The scan showed intense tracer uptake in the left frontal lobe lesion with severe edema, which was consistent with recurrence. Our case underscores the role of <sup>68</sup>Ga PSMA 11 PET/CT imaging of suspected glioblastoma recurrence which is the initial step in GBM theranostics with PSMA.

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Publication Details

Journal
Indian Journal of Nuclear Medicine
Published
2025-03-01
DOI
https://doi.org/10.4103/ijnm.ijnm_126_24
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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article

68Ga-PSMA PET/CT in a case of recurrent Glioblastoma

Madhavi Tripathi, G B Priyanka, Kunhi Parambath Haresh, Arunachalam Raghupathi Vishnu
Indian Journal of Nuclear Medicine
Glioma Diagnosis and Treatment
article

68Ga-PSMA PET/CT in a case of recurrent Glioblastoma

Madhavi Tripathi, G B Priyanka, Kunhi Parambath Haresh, Arunachalam Raghupathi Vishnu
article en

Abstract

Glioblastoma multiforme (GBM) is a high-grade brain tumor with a high recurrence rate. We present the case of a 57-year-old man with left frontal lobe GBM who was operated on and received radiation therapy in June 2023 and was referred for <sup>68</sup>Ga-PSMA 11 PET/CT with a clinical suspicion of recurrence. The scan showed intense tracer uptake in the left frontal lobe lesion with severe edema, which was consistent with recurrence. Our case underscores the role of <sup>68</sup>Ga PSMA 11 PET/CT imaging of suspected glioblastoma recurrence which is the initial step in GBM theranostics with PSMA.

Indian Journal of Nuclear MedicineVol. 40(2)
All India Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 78%
Glioma Diagnosis and Treatment
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