Hesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice
Hesperetin exerts renoprotective effects against I/R-induced AKI by improving renal function and inhibiting ferroptosis. Its therapeutic potential may be attributed to modulation of the Src, making it a promising candidate for AKI treatment.
Authors
- Zengying Liu
- Xiaoyu Xie (ORCID: https://orcid.org/0000-0002-1852-8546)
- Chen Guan (ORCID: https://orcid.org/0000-0002-3709-1247)
- Ningxin Zhang (ORCID: https://orcid.org/0000-0002-6258-9047)
- Yan Xu (ORCID: https://orcid.org/0000-0003-2049-3976)
- Chenyu Li (ORCID: https://orcid.org/0000-0002-5402-584X)
- Liting Wang (ORCID: https://orcid.org/0000-0001-6146-2549)
- Chengyu Yang (ORCID: https://orcid.org/0000-0002-1505-754X)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-06-29
- DOI
- https://doi.org/10.1080/0886022x.2025.2523573
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Qingdao Key Health Discipline Development Fund
- National Natural Science Foundation of China