Age-Related Changes in Antimülerian Hormone Levels: A Study of Ovarian Reserve in Pollog Region Women

The level of anti-Müllerian hormone (AMH) has become an important element in the initial investigation of female patients. Reproductive aging in women is primarily based on the decline in oocyte numbers over time. In principle, oocytes are non-reproductive; some oocytes mature and ovulate. Thus, AMH is clinically useful as a screening tool for diminished ovarian reserve. This study aims to evaluate the influence of age on serum AMH levels in women in the Polog region. The study is retrospective. The patients included in the study were classified into 3 groups according to age. Patient samples were analyzed using the ELFA technique on the Vidas analyzer using the sandwich immunological method. From statistical analysis of the data, it is observed that there is a significant statistical difference between group 1 (41 years) where the p value is 0.0005. A significant difference was also observed between group 2 (21 - 40 years) and group 3 (>41 years), with a p value < 0.0001. With a p value of p = 0.33, no significant statistical difference was found between group 1 (<20 years) and group 2 (21 - 40 years). Increasing age has a significant impact on decreasing levels of AMH, which reflects a woman’s ovarian reserve. After age 35, the decline in AMH is more rapid, highlighting the importance of early fertility consultations and possible treatment options.