Thermo-responsive nano-hydrogel-based delivery of Saikosaponin a to enhance anti-PD-1 therapy in osteosarcoma
The combination of Gel@PLGA@SSA@FA with pembrolizumab shows strong synergistic anti-tumor effects, offering a promising and biocompatible strategy for enhanced OS therapy.
Authors
- Haijun Feng
- Jianwei Zhou (ORCID: https://orcid.org/0000-0002-4146-7171)
- Yan-Qiang Chen
- Jingsheng Liu (ORCID: https://orcid.org/0000-0002-1424-428X)
- Kang Li (ORCID: https://orcid.org/0000-0002-9913-5954)
Institutions
- The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Nanomedicine
- Published
- 2025-06-29
- DOI
- https://doi.org/10.1080/17435889.2025.2526322
- Citations
- 2
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 1.35