Low Testosterone Among Males in Opioid Agonist Therapy and Its Association With Fatigue and Psychological Distress
Eighty percent of males receiving OAT had low testosterone levels. However, testosterone levels were not associated with symptoms of fatigue or psychological distress. These findings should be interpreted with caution due to suboptimal power and potential influence of confounding. Further research is warranted to clarify the clinical significance of biochemical threshold values for low testosterone levels and their relationship to specific clinical symptoms in the OAT population.
Authors
- Kjell Arne Johansson (ORCID: https://orcid.org/0000-0001-8912-8710)
- Elinor Vogt (ORCID: https://orcid.org/0000-0001-9810-987X)
- Else‐Marie Løberg (ORCID: https://orcid.org/0000-0002-4243-5067)
- Fatemeh Chalabianloo (ORCID: https://orcid.org/0000-0003-1242-1972)
- Jørn Henrik Vold (ORCID: https://orcid.org/0000-0001-8701-7638)
- Paal Methlie (ORCID: https://orcid.org/0000-0003-0548-0034)
- Karl Trygve Druckrey-Fiskaaen (ORCID: https://orcid.org/0000-0002-2905-0613)
- Lars Thore Fadnes (ORCID: https://orcid.org/0000-0001-8757-2092)
- Anne Taraldsen Heldal
Institutions
- Haukeland University Hospital (NO)
- University of Bergen (NO)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2025-06-28
- DOI
- https://doi.org/10.1210/jendso/bvaf114
- Citations
- 1
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Helse Vest
- Norges Forskningsråd
- Haukeland Universitetssjukehus