Pharmacological basis for medicinal use of Cymbopogon proximus Hochst. ex A. Rich. Essential oil in hyperactive gastrointestinal disorders
These results suggest that EOCP produces antidiarrheal and antispasmodic effects, possibly mediated via direct effect on intestinal smooth musclesf followed by dual inhibition of muscarinic receptors and Ca<sup>++</sup> channels, thus providing a pharmacological basis for its traditional use in hyperactive gut disorders such as diarrhea and spasms.
Authors
- Maged S. Abdel‐Kader (ORCID: https://orcid.org/0000-0002-5128-2656)
- Faisal F. Albaqami (ORCID: https://orcid.org/0000-0001-9343-5713)
- Najeeb Ur Rehman (ORCID: https://orcid.org/0000-0001-6925-7697)
- Hassan N. Althurwi (ORCID: https://orcid.org/0000-0003-3548-0852)
Institutions
- Prince Sattam Bin Abdulaziz University (SA)
- Alexandria University (EG)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fphar.2025.1533511
- Citations
- 2
- Primary Topic
- Essential Oils and Antimicrobial Activity
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- Prince Sattam bin Abdulaziz University