Long-term survival in advanced pulmonary large-cell neuroendocrine carcinoma after multi-line immunochemotherapy and anti-angiogenic therapy: a case report
This case illustrates the potential for long-term survival in advanced PLCNEC through intensive, multi-line combination therapies. The favorable outcome observed in this patient supports further investigation of such combination strategies in clinical studies.
Authors
- Hongming Wang (ORCID: https://orcid.org/0000-0002-2207-8015)
- Nuoni Wang
- Zhijun Wu (ORCID: https://orcid.org/0000-0002-8959-5076)
- Yangfeng Du
- Xiaoyang Liu (ORCID: https://orcid.org/0000-0002-1202-6764)
- Shiyan Li (ORCID: https://orcid.org/0000-0002-5974-1466)
- Jiang Zheng (ORCID: https://orcid.org/0009-0000-6181-4110)
- Zemin Xiao (ORCID: https://orcid.org/0009-0007-4716-1062)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-4835-8541)
Institutions
- Central South University (CN)
- The First People's Hospital of Changde (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fimmu.2025.1618672
- Citations
- 1
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 1.35