Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments
Results reveal that bone and muscle size, total and cortical content, and trabecular density are impaired in children with CP and CP-like conditions; however, cortical mineralization is not impaired. Therefore, the heightened risk of fragility fractures in children and adolescents with CP and CP-like conditions is likely due to smaller and thinner bone structure. Future investigation into bone microarchitecture is warranted.
Authors
- Leigh Gabel (ORCID: https://orcid.org/0000-0002-7429-2750)
- Elizabeth G. Condliffe (ORCID: https://orcid.org/0000-0002-0178-616X)
- Erin Hodgson
Institutions
- Allen Institute for Brain Science (US)
- University of Calgary (CA)
- Alberta Children's Hospital (CA)
- Alberta Bone and Joint Health Institute (CA)
- Ontario Brain Institute (CA)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fendo.2025.1620573
- Primary Topic
- Cerebral Palsy and Movement Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alberta Health Services