Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments

Results reveal that bone and muscle size, total and cortical content, and trabecular density are impaired in children with CP and CP-like conditions; however, cortical mineralization is not impaired. Therefore, the heightened risk of fragility fractures in children and adolescents with CP and CP-like conditions is likely due to smaller and thinner bone structure. Future investigation into bone microarchitecture is warranted.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-06-30
DOI
https://doi.org/10.3389/fendo.2025.1620573
Primary Topic
Cerebral Palsy and Movement Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments

Leigh Gabel, Elizabeth G. Condliffe, Erin Hodgson
Frontiers in Endocrinology
Cerebral Palsy and Movement Disorders
article

Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments

Leigh Gabel, Elizabeth G. Condliffe, Erin Hodgson
article en

Abstract

Results reveal that bone and muscle size, total and cortical content, and trabecular density are impaired in children with CP and CP-like conditions; however, cortical mineralization is not impaired. Therefore, the heightened risk of fragility fractures in children and adolescents with CP and CP-like conditions is likely due to smaller and thinner bone structure. Future investigation into bone microarchitecture is warranted.

Frontiers in EndocrinologyVol. 16
Allen Institute for Brain Science (US), University of Calgary (CA), Alberta Children's Hospital (CA), Alberta Bone and Joint Health Institute (CA), Ontario Brain Institute (CA)
Alberta Health Services
Openalex Percentile: Top 81%
Cerebral Palsy and Movement Disorders
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Smaller and thinner long bones in children and adolescents with cerebral palsy and other neuromotor impairments — Leigh Gabel, Elizabeth G. Condliffe, et al. · Frontiers in Endocrinology (2025) | TGRS Research Map | TGRS