LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis
NEAT1 promotes EMT in nasal polyp epithelial cells by modulating the miR-199-3p/PAK4 axis, highlighting its potential as a diagnostic biomarker and therapeutic target in CRSwNP.
Authors
- Chao Yuan (ORCID: https://orcid.org/0000-0003-1306-2094)
- Shuman Li (ORCID: https://orcid.org/0000-0002-1627-4175)
- Bo‐Wen Zheng (ORCID: https://orcid.org/0000-0002-9308-3794)
- Yucheng Yang (ORCID: https://orcid.org/0000-0002-2413-2935)
- Yu Jiang (ORCID: https://orcid.org/0000-0001-7036-0384)
- Yalan Zhang (ORCID: https://orcid.org/0000-0003-3185-2305)
- Yi Zhao (ORCID: https://orcid.org/0009-0005-2905-5675)
- Tao Lu (ORCID: https://orcid.org/0000-0001-6749-1674)
- Yang Shen (ORCID: https://orcid.org/0000-0003-4714-0839)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Cancer Hospital (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-30
- DOI
- https://doi.org/10.3389/fimmu.2025.1613179
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chongqing University
- Chongqing Medical University
- Natural Science Foundation of Chongqing
- Centre Scientifique et Technique du Bâtiment