Struma ovarii mimicking ovarian malignancy: a case report

Struma ovarii is a rare form of monodermal ovarian teratoma composed predominantly of mature thyroid tissue. Although benign in most cases, it can present with ascites and elevated serum CA125 levels, mimicking ovarian carcinoma. We report the case of a 38-year-old woman with a complex ovarian mass, ascites, and an elevated CA125 level-an initial presentation highly suggestive of malignancy that was ultimately diagnosed as benign struma ovarii following surgical intervention. This case underscores how struma ovarii, though uncommon, can masquerade as ovarian cancer and may even be discovered incidentally in an asymptomatic, premenopausal patient.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-05-31
DOI
https://doi.org/10.1093/jscr/rjaf439
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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Struma ovarii mimicking ovarian malignancy: a case report

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Journal of Surgical Case Reports
Ovarian cancer diagnosis and treatment
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Struma ovarii mimicking ovarian malignancy: a case report

Ana Gomes da Costa, Adalgisa Guerra, Giulia Innocenti Bruni, João Casanova, Ana Catarino, Marta Tripepi
article en

Abstract

Struma ovarii is a rare form of monodermal ovarian teratoma composed predominantly of mature thyroid tissue. Although benign in most cases, it can present with ascites and elevated serum CA125 levels, mimicking ovarian carcinoma. We report the case of a 38-year-old woman with a complex ovarian mass, ascites, and an elevated CA125 level-an initial presentation highly suggestive of malignancy that was ultimately diagnosed as benign struma ovarii following surgical intervention. This case underscores how struma ovarii, though uncommon, can masquerade as ovarian cancer and may even be discovered incidentally in an asymptomatic, premenopausal patient.

Journal of Surgical Case ReportsVol. 2025(6)
University of Padua (IT), University of Ferrara (IT), Hospital da Luz (PT)
Good health and well-being
Openalex Percentile: Top 78%
Ovarian cancer diagnosis and treatment
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