Acute Hemichorea in a Young Patient Secondary to Ischemic Infarction in the Right Lentiform Nucleus: A Case Report

Chorea is a hyperkinetic movement disorder characterised by brief, unpredictable, dance-like involuntary movements involving multiple body parts. Hemichorea is its unilateral variant, affecting one side of the body. Both can arise from diverse aetiologies, including genetic, vascular, metabolic, autoimmune, drug-induced, and infectious causes. We report the case of a 31-year-old male with no significant past medical history who developed sudden-onset, left-sided hemichorea and homonymous hemianopia. Brain MRI demonstrated an acute right lentiform infarct, predominantly involving the globus pallidus. The patient improved markedly within 24 hours following the initiation of antiplatelet therapy. Further investigations revealed a Stage 2A-shunt patent foramen ovale, deemed the likely aetiology. This case underscores the importance of recognising hemichorea as a rare but possible manifestation of acute ischaemic stroke and highlights the need for comprehensive diagnostic evaluation in young patients presenting with atypical stroke symptoms.

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Journal
Cureus
Published
2025-06-29
DOI
https://doi.org/10.7759/cureus.86969
Primary Topic
Neurological and metabolic disorders
Type
article
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article

Acute Hemichorea in a Young Patient Secondary to Ischemic Infarction in the Right Lentiform Nucleus: A Case Report

Babiker Ahmed Mohamed, Christos Nikola, Yee Mon Thu, Ali Altahiry
Cureus
Neurological and metabolic disorders
article

Acute Hemichorea in a Young Patient Secondary to Ischemic Infarction in the Right Lentiform Nucleus: A Case Report

Babiker Ahmed Mohamed, Christos Nikola, Yee Mon Thu, Ali Altahiry
article en

Abstract

Chorea is a hyperkinetic movement disorder characterised by brief, unpredictable, dance-like involuntary movements involving multiple body parts. Hemichorea is its unilateral variant, affecting one side of the body. Both can arise from diverse aetiologies, including genetic, vascular, metabolic, autoimmune, drug-induced, and infectious causes. We report the case of a 31-year-old male with no significant past medical history who developed sudden-onset, left-sided hemichorea and homonymous hemianopia. Brain MRI demonstrated an acute right lentiform infarct, predominantly involving the globus pallidus. The patient improved markedly within 24 hours following the initiation of antiplatelet therapy. Further investigations revealed a Stage 2A-shunt patent foramen ovale, deemed the likely aetiology. This case underscores the importance of recognising hemichorea as a rare but possible manifestation of acute ischaemic stroke and highlights the need for comprehensive diagnostic evaluation in young patients presenting with atypical stroke symptoms.

CureusVol. 17(6)
Barts Health NHS Trust (GB)
Gender equality
Openalex Percentile: Top 77%
Neurological and metabolic disorders
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Acute Hemichorea in a Young Patient Secondary to Ischemic Infarction in the Right Lentiform Nucleus: A Case Report — Babiker Ahmed Mohamed, Christos Nikola, et al. · Cureus (2025) | TGRS Research Map | TGRS