Successful Management of Acyclovir-Induced Nephrotoxicity in a Patient with Varicella Zoster Virus Encephalitis in a Resource-Limited Setting- A Case Report

This case report describes a 42-year-old male patient who developed acyclovir-induced nephrotoxicity while being treated for varicella zoster virus encephalitis. The case report underscores the challenges faced in a low-income setting where continuing acyclovir at a reduced dose was necessary due to the lack of alternative antiviral treatments. The patient's condition was successfully managed through careful dose adjustment and intensive monitoring, resulting in a gradual recovery of renal function.

Authors

Publication Details

Journal
Journal of Tropical Health
Published
2025-06-30
DOI
https://doi.org/10.4038/joth.v1i2.8
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Successful Management of Acyclovir-Induced Nephrotoxicity in a Patient with Varicella Zoster Virus Encephalitis in a Resource-Limited Setting- A Case Report

Chamara Sarathchandra, Thilina Rathnasekara, Supun Wedasingha, Hemal Senanayake et al.
Journal of Tropical Health
Herpesvirus Infections and Treatments
article

Successful Management of Acyclovir-Induced Nephrotoxicity in a Patient with Varicella Zoster Virus Encephalitis in a Resource-Limited Setting- A Case Report

Chamara Sarathchandra, Thilina Rathnasekara, Supun Wedasingha, Hemal Senanayake, R. P. V. J. Rajapaksha
article en

Abstract

This case report describes a 42-year-old male patient who developed acyclovir-induced nephrotoxicity while being treated for varicella zoster virus encephalitis. The case report underscores the challenges faced in a low-income setting where continuing acyclovir at a reduced dose was necessary due to the lack of alternative antiviral treatments. The patient's condition was successfully managed through careful dose adjustment and intensive monitoring, resulting in a gradual recovery of renal function.

Journal of Tropical HealthVol. 1(2)
Openalex Percentile: Top 78%
Herpesvirus Infections and Treatments
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Successful Management of Acyclovir-Induced Nephrotoxicity in a Patient with Varicella Zoster Virus Encephalitis in a Resource-Limited Setting- A Case Report — Chamara Sarathchandra, Thilina Rathnasekara, et al. · Journal of Tropical Health (2025) | TGRS Research Map | TGRS