Narrative Review on Postoperative Pain Management Following Spine Surgery

Postoperative pain is an inevitable consequence of spine surgery, yet there remains no universal consensus on the optimal pain management strategy. The complexity of spine procedures, coupled with patient variability, necessitates a multifaceted approach to pain control. Over time, numerous strategies have emerged, each with varying levels of effectiveness. Pharmacological approaches, including multimodal analgesia, local anesthetic infusions, and gabapentinoids, provide relief for both acute and chronic pain. Additionally, perioperative strategies such as enhanced recovery after surgery (ERAS) protocols have demonstrated benefits in optimizing pain control and recovery outcomes. Beyond pharmacological interventions, physical therapy has become a cornerstone of postoperative pain management, aiding in functional recovery and reducing reliance on medications. For patients with refractory or chronic pain, neuromodulatory techniques such as spinal cord stimulation and intrathecal injections offer alternative solutions. Despite the breadth of evidence-based strategies available, limitations persist, including opioid dependence, the complexity of multimodal regimens leading to suboptimal compliance, and cases of refractory pain. These challenges underscore the importance of tailoring pain management approaches to individual patient needs, ensuring a balance between effectiveness and safety. This narrative review of evidence seeks to explore the multifaceted nature of pain management following spine surgery, highlighting the challenges and evolving strategies in optimizing patient outcomes.

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Publication Details

Journal
Neurospine
Published
2025-06-29
DOI
https://doi.org/10.14245/ns.2550410.205
Citations
6
Primary Topic
Anesthesia and Pain Management
Type
article
Field-Weighted Citation Impact
12.04
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article

Narrative Review on Postoperative Pain Management Following Spine Surgery

Ryan Mattie, Michael W. Madsen, Chuan-ding Yu, Oluwafemi Kehinde Akande et al.
6 citations
Neurospine
Anesthesia and Pain Management
12.04
article

Narrative Review on Postoperative Pain Management Following Spine Surgery

Ryan Mattie, Michael W. Madsen, Chuan-ding Yu, Oluwafemi Kehinde Akande, David W. Lee, Michael Oh
article en
6 citations

Abstract

Postoperative pain is an inevitable consequence of spine surgery, yet there remains no universal consensus on the optimal pain management strategy. The complexity of spine procedures, coupled with patient variability, necessitates a multifaceted approach to pain control. Over time, numerous strategies have emerged, each with varying levels of effectiveness. Pharmacological approaches, including multimodal analgesia, local anesthetic infusions, and gabapentinoids, provide relief for both acute and chronic pain. Additionally, perioperative strategies such as enhanced recovery after surgery (ERAS) protocols have demonstrated benefits in optimizing pain control and recovery outcomes. Beyond pharmacological interventions, physical therapy has become a cornerstone of postoperative pain management, aiding in functional recovery and reducing reliance on medications. For patients with refractory or chronic pain, neuromodulatory techniques such as spinal cord stimulation and intrathecal injections offer alternative solutions. Despite the breadth of evidence-based strategies available, limitations persist, including opioid dependence, the complexity of multimodal regimens leading to suboptimal compliance, and cases of refractory pain. These challenges underscore the importance of tailoring pain management approaches to individual patient needs, ensuring a balance between effectiveness and safety. This narrative review of evidence seeks to explore the multifaceted nature of pain management following spine surgery, highlighting the challenges and evolving strategies in optimizing patient outcomes.

NeurospineVol. 22(2)
Fullerton College (US), California State University, Fullerton (US), University of California, Irvine (US), Neurological Surgery (US), Total Rehab (US)
Good health and well-being
Openalex Percentile: Top 1%
Anesthesia and Pain Management
12.04
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Narrative Review on Postoperative Pain Management Following Spine Surgery — Ryan Mattie, Michael W. Madsen, et al. · Neurospine (2025) | TGRS Research Map | TGRS