Xanthogranulomatous metritis in a Korean short-haired cat: a case report

A case of xanthogranulomatous metritis in a 5-year-old Korean short-haired cat is presented. Yellowish-white nodules, 1 to 2 cm in diameter and protruding from the perimetrium, were detected. Histopathological examination revealed extensive inflammatory nodules extending from the endometrium to the perimetrium. The inflammatory nodules primarily consisted of numerous macrophages, along with a smaller number of multinucleated giant cells and lymphocytes. Immunostaining for Iba-1 and Major Histocompatibility Complex class II showed positive reactions in macrophages and multinucleated giant cells. Based on these findings, a diagnosis of xanthogranulomatous metritis in the feline uterus was diagnosed. Because xanthogranulomatous metritis could be clinically diagnosed as a neoplastic lesion, it is considered to have important obstetric value in the differential diagnosis.