ON THE SIGNIFICANCE OF THE SCORE-2 RISK SCALE FOR CARDIOVASCULAR COMPLICATIONS AMONG PATIENTS WITH PREDIABETES

The aim of the study is to consider and evaluate the value of the SCORE-2 cardiovascular risk scale among patients with prediabetes. Material and methods of the study. The study included 45 people aged 40 to 65 years, including 25 men with an average age of 59.3±8.2 years and 20 women with an average age of 55.2±7.1 years. The control group consisted of 20 healthy people. Research methods: included general clinical methods, biochemical tests (fasting blood glucose level and 2 hours after a meal, glycated hemoglobin, bilirubin, both direct and indirect, ALT, AST, PTI, coagulogramm, C-reactive protein, urea, creatinine, lipid spectrum), hormonal studies (if necessary, insulin and C-peptide levels in the blood) and instrumental methods: ECG, ultrasound of the endocrine glands and internal organs, chest X-ray and others. Research results. When assessed using the SCORE2 scale, patients were divided into risk groups: 17 of them were in the low risk group, 15 in the moderate risk group, 7 in the high risk group and 6 in the very high risk group. The estimated risk of death and non-fatal CVD ranged from 0.3% to 53.2%, with a mean value of 8.8±7.5%. According to the SCORE2 scale, all patients were classified into the high and very high risk categories, comprising 18 and 27 patients, respectively. Conclusions. 1. The SCORE2 scale, used to calculate non-high-density lipoprotein cholesterol (non-HDL-C) levels, provides a more individualized risk assessment, showing more unfavorable results among the Uzbek ethnic group. The SCORE2 system has a more differentiated approach to determining individual cardiovascular risk.