Effects of FECH Gene Polymorphisms and Serum Ferrochelatase Levels on Antituberculosis Drug‐Induced Liver Injury in China
This study is the first to explore the relationships between SNPs in the FECH gene, serum ferrochelatase levels, and ATLI in China, and SNP rs536560 in the FECH gene, baseline ferrochelatase level, and liver disease history may be associated with susceptibility to ATLI.
Authors
- Lihuan Lu
- Jing-Ru C. Cheng (ORCID: https://orcid.org/0000-0002-2281-0288)
- Hongqiu Pan (ORCID: https://orcid.org/0000-0002-7091-3230)
- Shaowen Tang (ORCID: https://orcid.org/0000-0001-5879-8594)
- Honggang Yi
- Ruina Chen
- Meiling Zhang (ORCID: https://orcid.org/0000-0002-0996-9702)
- Nannan Wang (ORCID: https://orcid.org/0000-0002-9013-0612)
- Xiaomin He (ORCID: https://orcid.org/0000-0002-6079-1014)
Institutions
- Jiangsu University (CN)
- Taixing People's Hospital (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Changshu No.1 People's Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Fundamental and Clinical Pharmacology
- Published
- 2025-06-29
- DOI
- https://doi.org/10.1111/fcp.70034
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China