THE ROLE OF THE STEREOFUNCTIONAL ORGANIZATION OF THE FEMALE BODY IN THE FORMATION OF STRESS RESISTANCE DURING PREGNANCY

The peculiarities of the adaptive specificity of regulatory processes in pregnant women who have lived in the war zone for a long time are of particular scientific interest due to the high stress vulnerability of this category of subjects. Morpho-functional asymmetries of the female body (lateral phenotype – LF) are an important constitutional feature mediating stress resistance, in the formation of which the leading positions belong to the nervous and humoral circuits of regulation. The aim is to study the characteristics of hormonal status in pregnant women with different levels of stress caused by prolonged residence in a war zone, depending on the nature of the lateral constitution. When determining the nature of exercise therapy in pregnant women with various stress levels, the dominance of low stress levels was found mainly in right exercise, high in women with ambidextrous exercise. A decrease in the level of 6-sulfatoxymelatonin (by an average of 35,1 %) and sex hormones (by 12,6 %) was found in pregnant women from the Donetsk and Lugansk People's Republics (DPR and LPR) compared with residents of the Rostov region. Depending on the nature of exercise therapy, the highest levels of hormones of the stress-realizing group were found in women with ambidextrous exercise therapy. With the ambidextral type of lateral constitution, with a more pronounced production of stress-realizing hormones and a decrease in melatonin production, high stress levels are significantly more likely to develop, regardless of the region of residence of pregnant women, which indicates the greatest stress vulnerability of this type of lateral constitution compared to the polar right and left lateral phenotypes. The higher frequency of high stress levels (1,8 times) in pregnant women with an ambidextrous phenotype from the Donetsk and Lugansk People's Republics compared with residents of the Rostov region indicates a more pronounced decrease in stress resistance of pregnant women who lived in the region of military operations before resettlement.