[Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2α-ATF4-CHOP pathway].
MCC induce endoplasmic reticulum stress and apoptosis in rat brain tissues, for which CBD, especially at a high dose, provides neuroprotective effects by inhibiting endoplasmic reticulum stress and cell apoptosis.
Authors
- Yujia Yang (ORCID: https://orcid.org/0000-0002-9130-7619)
- Yaling Wu (ORCID: https://orcid.org/0000-0002-7630-3441)
- Zhaoda Duan (ORCID: https://orcid.org/0009-0001-7902-7251)
- Lifang Yang (ORCID: https://orcid.org/0000-0002-7562-7620)
- Chang‐Xi Yu (ORCID: https://orcid.org/0000-0001-8115-0411)
- Jianyun Yu (ORCID: https://orcid.org/0000-0002-5211-0581)
- Chunyun Wu (ORCID: https://orcid.org/0000-0002-6349-4103)
- Liteng Yang (ORCID: https://orcid.org/0000-0002-0436-0287)
Institutions
- Kunming Medical University (CN)
- Shuozhou Central Hospital (CN)
- Yunnan Maternal and Child Health (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.06.13
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article