[Down-regulation of ACADM-mediated lipotoxicity inhibits invasion and metastasis of estrogen receptor-positive breast cancer cells].
Down-regulation of ACADM inhibits migration and invasion ability of estrogen receptor-positive breast cancer cells by lowering lipotoxicity and impairing mitochondrial function through the ROS/PI3K/AKT pathway.
Authors
- Ruiting Xian
- Jia-Hao Li (ORCID: https://orcid.org/0009-0003-2889-0965)
- Rong Li (ORCID: https://orcid.org/0000-0001-9835-6563)
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.06.06
- Primary Topic
- Cancer Treatment and Pharmacology
- Type
- article