[ATF3 regulates inflammatory response in atherosclerotic plaques in mice through the NF-κB signaling pathway].
AS promotes ATF3 expression, and ATF3 deficiency exacerbates AS progression by enhancing plaque inflammation via activating the NF-κB pathway, suggesting the potential of ATF3 as a therapeutic target for AS.
Authors
- Yun Wang (ORCID: https://orcid.org/0000-0002-4346-0096)
- Guojie Liu (ORCID: https://orcid.org/0000-0001-7213-5404)
- Guowei Tang
- Peng Jin (ORCID: https://orcid.org/0000-0001-5315-4343)
- Changwu Wan
- C. Y. Le (ORCID: https://orcid.org/0009-0001-6758-021X)
- Jiuyang Ding (ORCID: https://orcid.org/0000-0001-9089-1756)
- Bing Xia (ORCID: https://orcid.org/0000-0002-9178-5493)
- Jie Wang (ORCID: https://orcid.org/0000-0002-1659-0637)
Institutions
- Guiyang Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.06.03
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article