[Ecliptasaponin A ameliorates DSS-induced colitis in mice by suppressing M1 macrophage polarization <i>via</i> inhibiting the JAK2/STAT3 pathway].
ESA alleviates DSS-induced colitis in mice by suppressing JAK2/STAT3-mediated M1 macrophage polarization and mitigating inflammation-driven intestinal barrier damage.
Authors
- Zhijun Geng (ORCID: https://orcid.org/0000-0002-4040-5622)
- Keni Zhang
- Jianguo Hu (ORCID: https://orcid.org/0000-0003-0207-9536)
- Lin Yin
- Lixia Yin (ORCID: https://orcid.org/0009-0005-6852-5713)
- Jing Li (ORCID: https://orcid.org/0000-0002-1690-9548)
- Qiao Tong (ORCID: https://orcid.org/0000-0003-3087-4211)
- Chuanwang Song (ORCID: https://orcid.org/0000-0002-7374-0443)
- Minzhu Niu
Institutions
- Bengbu Medical College (CN)
- Suzhou Municipal Hospital (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.06.19
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article