Impact of Individualized Nutritional Interventions on the Effect of Nutritional Improvement in Neurosevere Patients

Neurocritical care patients have highly heterogeneous nutritional needs due to metabolic disorders, organ dysfunction, and other pathophysiologic characteristics. Current nutritional support studies mostly focus on the effects of single nutritional formulas or isolated nutrients. Also, there is a lack of systematic comparisons between individualized nutritional interventions and fixed-formula regimens regarding clinical outcomes. This study aimes to investigate the differences in the effects of individualized nutritional interventions and fixed formulas (Jevity, Glucerna) on the improvement of nutritional metabolic indexes in neurocritical care patients. The study included 120 neurologically ill patients, divided into three groups: Jevity, Glucerna, and individualized nutrition. It compared the cystatin/creatinine ratio (SI), albumin, and hemoglobin before and after the 2-week intervention in the three groups. The results show that individualized nutritional support can improve the nutritional status of neurocritical care patients more effectively, but its modulating effect on albumin and long-term prognosis still need to be verified by large-sample studies.