The Role of Resistance Exercise in Skeletal Muscle Recovery, and Changes in Igf-1 Secretion

Skeletal muscle injury has been a significant problem that people face, as there are limited solutions to reform it. As there are already various amounts of reviews and researches focusing on in vitro developments, this reviews mainly focuses on how resistance exercise enhances skeletal muscle recovery in humans by making large amounts of insulin growth factor I (IGF-I). The role of IGF-I and how it enhances skeletal muscular recovery will be clarified in this review. This paper only focuses on humans in post-exercise conditions, and how increased muscle mass is beneficial for muscular recovery. As it has been a controversial question of whether resting is more beneficial after injury or whether other components could enhance and hasten muscular recovery, this review points out the differences in composition of IGF-I in resistance exercise and resting stages. The result shows that resistance exercise is a source that stimulates IGF-I concentration in humans bodies, which encourages the synthesis of muscle fibers, resistance exercise can be proven as a non-pathological tool that is beneficial for muscular recovery.

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Publication Details

Journal
Theoretical and Natural Science
Published
2025-06-27
DOI
https://doi.org/10.54254/2753-8818/2025.ld24444
Primary Topic
Exercise and Physiological Responses
Type
article
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article

The Role of Resistance Exercise in Skeletal Muscle Recovery, and Changes in Igf-1 Secretion

Shengli Zhao
Theoretical and Natural Science
Exercise and Physiological Responses
article

The Role of Resistance Exercise in Skeletal Muscle Recovery, and Changes in Igf-1 Secretion

Shengli Zhao
article en

Abstract

Skeletal muscle injury has been a significant problem that people face, as there are limited solutions to reform it. As there are already various amounts of reviews and researches focusing on in vitro developments, this reviews mainly focuses on how resistance exercise enhances skeletal muscle recovery in humans by making large amounts of insulin growth factor I (IGF-I). The role of IGF-I and how it enhances skeletal muscular recovery will be clarified in this review. This paper only focuses on humans in post-exercise conditions, and how increased muscle mass is beneficial for muscular recovery. As it has been a controversial question of whether resting is more beneficial after injury or whether other components could enhance and hasten muscular recovery, this review points out the differences in composition of IGF-I in resistance exercise and resting stages. The result shows that resistance exercise is a source that stimulates IGF-I concentration in humans bodies, which encourages the synthesis of muscle fibers, resistance exercise can be proven as a non-pathological tool that is beneficial for muscular recovery.

Theoretical and Natural ScienceVol. 117(1)
Shanghai International Studies University (CN)
Openalex Percentile: Top 81%
Exercise and Physiological Responses
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The Role of Resistance Exercise in Skeletal Muscle Recovery, and Changes in Igf-1 Secretion — Shengli Zhao · Theoretical and Natural Science (2025) | TGRS Research Map | TGRS