Anti–PD-1 antibody with or without capecitabine as maintenance therapy after first-line therapy of recurrent or metastatic nasopharyngeal carcinoma

Anti-PD-1 antibody plus capecitabine maintenance therapy improved PFS with manageable toxicities in patients with RM-MPC following first-line immunochemotherapy, particularly in those with pre-treatment EBV DNA >12 400 copies/mL and undetectable post-treatment levels.

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Publication Details

Journal
The Oncologist
Published
2025-06-24
DOI
https://doi.org/10.1093/oncolo/oyaf188
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00

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article

Anti–PD-1 antibody with or without capecitabine as maintenance therapy after first-line therapy of recurrent or metastatic nasopharyngeal carcinoma

Hai‐Qiang Mai, Jiayi Shen, Lin‐Quan Tang, Jie Chen et al.
The Oncologist
Cancer Immunotherapy and Biomarkers
article

Anti–PD-1 antibody with or without capecitabine as maintenance therapy after first-line therapy of recurrent or metastatic nasopharyngeal carcinoma

Hai‐Qiang Mai, Jiayi Shen, Lin‐Quan Tang, Jie Chen, Shanshan Guo, Yi-Fu Li, Li-Ting Liu, Hui Cheng, Bowen Shen, Pan Wang, Jing‐Yun Peng, Qiu-Yan Chen, Xue-Song Sun, Hao-Xiang Long, Yu Chen
article en

Abstract

Anti-PD-1 antibody plus capecitabine maintenance therapy improved PFS with manageable toxicities in patients with RM-MPC following first-line immunochemotherapy, particularly in those with pre-treatment EBV DNA >12 400 copies/mL and undetectable post-treatment levels.

The OncologistVol. 30(7)
Sun Yat-sen University (CN), Sun Yat-sen University Cancer Center (CN)
National Natural Science Foundation of China, Sun Yat-sen University, China Postdoctoral Science Foundation, National Science and Technology Major Project, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities, Basic and Applied Basic Research Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 77%
Cancer Immunotherapy and Biomarkers
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Anti–PD-1 antibody with or without capecitabine as maintenance therapy after first-line therapy of recurrent or metastatic nasopharyngeal carcinoma — Hai‐Qiang Mai, Jiayi Shen, et al. · The Oncologist (2025) | TGRS Research Map | TGRS