Advancing Age and Risk From the Elevated Atherogenic Index: Triglyceride (<scp>TG</scp>) to High‐Density Cholesterol (<scp>HDL</scp>‐C) Ratio
The association between the TG/HDL-C ratio (atherogenic index) and incident ASCVD steadily attenuates with age. In adults over 65, an elevated ratio may be associated with a lower risk of incident ASCVD. These findings may reflect changes in metabolic atherosclerotic risk or a survival effect associated with aging and require further investigation.
Authors
- Shangshu Zhao
- Manish Kumar (ORCID: https://orcid.org/0000-0003-0424-8858)
- George A. Kuchel (ORCID: https://orcid.org/0000-0001-8387-7040)
- Ariela R. Orkaby (ORCID: https://orcid.org/0000-0002-4297-6306)
- Karen P. Alexander (ORCID: https://orcid.org/0000-0003-4418-1424)
- Richard H. Fortinsky (ORCID: https://orcid.org/0000-0002-2013-719X)
- John A. Batsis (ORCID: https://orcid.org/0000-0002-0845-4416)
- Chia‐Ling Kuo (ORCID: https://orcid.org/0000-0003-4452-2380)
- P. A. Robinson (ORCID: https://orcid.org/0000-0002-5050-9804)
- Paul M. Thompson (ORCID: https://orcid.org/0000-0002-4720-8867)
Institutions
- University of North Carolina at Chapel Hill (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- University of Connecticut (US)
- Clinical Research Institute (US)
- Geriatric Research Education and Clinical Center (US)
- Marshfield Clinic (US)
- UConn Health (US)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2025-06-29
- DOI
- https://doi.org/10.1111/jgs.19607
- Citations
- 3
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 6.02