Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐<scp>GFAP</scp> Antibodies

The κ-FLC index alone cannot distinguish between autoimmune GFAP astrocytopathy and MS. We indicate a potential diagnostic and prognostic role of the λ-FLC index in GFAP astrocytopathy that needs confirmation in independent cohorts.

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Publication Details

Journal
Annals of Clinical and Translational Neurology
Published
2025-06-28
DOI
https://doi.org/10.1002/acn3.70103
Citations
1
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
1.47
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article

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Jeanne Benoit, Barbara Seitz‐Polski, Marion Crémoni, Élisabeth Maillart et al.
1 citations
Annals of Clinical and Translational Neurology
Multiple Sclerosis Research Studies
1.47
article

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Jeanne Benoit, Barbara Seitz‐Polski, Marion Crémoni, Élisabeth Maillart, Pauline Dumez, Mikaël Cohen, Cassandre Landes-Château, Jérôme Honnorat, Michaël Levraut, Christine Lebrun‐Frénay, Romain Marignier, Anne‐Laurie Pinto
article en
1 citations

Abstract

The κ-FLC index alone cannot distinguish between autoimmune GFAP astrocytopathy and MS. We indicate a potential diagnostic and prognostic role of the λ-FLC index in GFAP astrocytopathy that needs confirmation in independent cohorts.

Annals of Clinical and Translational NeurologyVol. 12(9)
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre Hospitalier Universitaire de Nice (FR), Sorbonne Université (FR), Centre de Recherche en Neurosciences de Lyon (FR), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), Hôpital Pierre Wertheimer (FR), Pitié-Salpêtrière Hospital (FR)
Good health and well-being
Openalex Percentile: Top 18%
Multiple Sclerosis Research Studies
1.47
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Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐<scp>GFAP</scp> Antibodies — Jeanne Benoit, Barbara Seitz‐Polski, et al. · Annals of Clinical and Translational Neurology (2025) | TGRS Research Map | TGRS