Basosquamous cell carcinoma in congenital nevus: case study in a young patient

Basosquamous cell carcinoma is a relatively rare skin neoplasm that combines characteristics of both basal cell and squamous cell carcinoma. It is currently recognized as a subtype of basal cell carcinoma with a much more aggressive behavior. Its clinical presentation is nonspecific, and its diagnosis is generally made only after a biopsy. It predominates in male patients during the seventh decade of life and tends to appear in photo-exposed regions. We present a 32-year-old male patient with no significant medical history who presented to the dermatology clinic with a mole on his left thigh since birth, which had been growing over the previous 12 months. The biopsy was compatible with typical metastatic basal cell carcinoma. Our patient's case shows an atypical presentation due to its location and its onset 40 years earlier than the average age reported in the literature.

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Publication Details

Journal
International Journal of Research in Dermatology
Published
2025-06-27
DOI
https://doi.org/10.18203/issn.2455-4529.intjresdermatol20252069
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
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article

Basosquamous cell carcinoma in congenital nevus: case study in a young patient

María Belén Proaño Bonifaz, Bertha Bayancela
International Journal of Research in Dermatology
Nonmelanoma Skin Cancer Studies
article

Basosquamous cell carcinoma in congenital nevus: case study in a young patient

María Belén Proaño Bonifaz, Bertha Bayancela
article en

Abstract

Basosquamous cell carcinoma is a relatively rare skin neoplasm that combines characteristics of both basal cell and squamous cell carcinoma. It is currently recognized as a subtype of basal cell carcinoma with a much more aggressive behavior. Its clinical presentation is nonspecific, and its diagnosis is generally made only after a biopsy. It predominates in male patients during the seventh decade of life and tends to appear in photo-exposed regions. We present a 32-year-old male patient with no significant medical history who presented to the dermatology clinic with a mole on his left thigh since birth, which had been growing over the previous 12 months. The biopsy was compatible with typical metastatic basal cell carcinoma. Our patient's case shows an atypical presentation due to its location and its onset 40 years earlier than the average age reported in the literature.

International Journal of Research in DermatologyVol. 11(4)
Hôpital Renée Sabran (FR), Armed Forces Hospital (SA)
Openalex Percentile: Top 78%
Nonmelanoma Skin Cancer Studies
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Basosquamous cell carcinoma in congenital nevus: case study in a young patient — María Belén Proaño Bonifaz, Bertha Bayancela · International Journal of Research in Dermatology (2025) | TGRS Research Map | TGRS