1,25-Dihydroxy vitamin D <sub>3</sub> inhibits LPS-mediated inflammatory responses in endometriosis
Collectively, these results underscore the potential of 1,25(OH)<sub>2</sub>D<sub>3</sub> as a therapeutic target for endometriosis <i>via</i> VDR-dependent endometrial homeostasis regulation, suppressing LPS-mediated inflammatory responses and NF-κB signaling pathway through VDR activation and IκBα stabilization.
Authors
- Hui‐Ling Lai (ORCID: https://orcid.org/0000-0002-4853-981X)
- Zhouzhou Liao
- Shuqin Chen (ORCID: https://orcid.org/0000-0002-8260-5809)
- Jianyu Ma (ORCID: https://orcid.org/0009-0001-5480-4528)
- Zhuang Jin (ORCID: https://orcid.org/0000-0002-3533-5324)
- Qiyu Zhong (ORCID: https://orcid.org/0000-0001-9335-8789)
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1080/07853890.2025.2523563
- Citations
- 5
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.49
Funders
- Natural Science Foundation of Guangdong Province