<scp>miR</scp> ‐134‐3p Deficiency‐Induced Methionine Metabolism Promotes Fibrosis via <scp>SLC25A33</scp> in <scp>OSF</scp>
In summary, the findings suggested that miR-134-3p is underexpressed in fibroblasts, which directly binds to SLC25A33, leading to degradation of SLC25A33 mRNAs. SLC25A33 induces methionine metabolism reprogramming to promote collagen synthesis through the mTOR pathway in OSF.
Authors
- Jing He
- Jiajun Huang (ORCID: https://orcid.org/0000-0002-1997-8514)
- Changyun Fang (ORCID: https://orcid.org/0000-0002-2879-6587)
- Tianru Yang (ORCID: https://orcid.org/0000-0002-4226-6048)
- Xinle Zhang
- M. Shao
- Mianfeng Yao (ORCID: https://orcid.org/0000-0002-7888-3873)
- Li Jiang (ORCID: https://orcid.org/0000-0002-1622-2623)
- Ziqiao Zheng (ORCID: https://orcid.org/0000-0002-5013-8281)
- Yao Sun (ORCID: https://orcid.org/0000-0002-7268-9201)
- Q. Li
Institutions
- Central South University (CN)
- Hunan University (CN)
- Xiangya Hospital Central South University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-06-28
- DOI
- https://doi.org/10.1111/jop.70003
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00