Design and Development of a Modular OPM-MEG Device Based on 3D Chinese Head Anthropometry

Magnetoencephalography (MEG) has emerged as a critical non-invasive neuroimaging modality in both clinical and research domains, owing to its exceptional spatiotemporal resolution and absence of ionizing radiation. Conventional MEG systems utilizing superconducting quantum interference devices (SQUIDs) are constrained by the necessity for cryogenic cooling, resulting in substantial operational complexity and maintenance costs. While optically pumped magnetometer (OPM) technology has enabled room-temperature operation, contemporary helmet designs present significant adaptability limitations - 3D-printed customized helmets incur prohibitive production expenses, while flexible alternatives suffer from compromised sensor positioning accuracy.This investigation proposes an innovative modular OPM-MEG system architecture that incorporates 3D cephalometric characteristics of Chinese populations with advanced electromagnetic shielding technology. The developed system incorporates an auto-adaptive sensor array featuring revolutionary mechanical configurations and optimized spatial arrangements, achieving remarkable improvements in device adaptability while maintaining superior measurement fidelity. Comprehensive theoretical modeling and computational simulations have substantiated the design's viability, yielding a pragmatic solution for clinical MEG applications. This advancement represents a significant contribution to the evolution of neuroimaging technologies and possesses profound implications for neuroscience research.