Photosensitivity induced by <i>Tribulus terrestris</i> extract supplement
We report a case of drug-induced photosensitivity potentially triggered by Tribulus terrestris, a supplement commonly used to enhance athletic performance and sexual function. To our knowledge, this is the first documented case linking T. terrestris to such a reaction in humans. Our findings are based on clinical presentation and objective on- and off-drug phototesting, which provide compelling evidence that T. terrestris may induce a photosensitivity reaction, particularly under ultraviolet A exposure. This case contributes important new insights into the safety profile of T. terrestris and underscores the need for clinicians to consider herbal supplements as possible culprits in drug-induced photosensitivity.
Authors
- Chee Hian Tan
- Robert Dawe
Institutions
- National Skin Centre (SG)
- Ninewells Hospital (GB)
Publication Details
- Journal
- Clinical and Experimental Dermatology
- Published
- 2025-06-20
- DOI
- https://doi.org/10.1093/ced/llaf286
- Primary Topic
- Phytochemical Studies and Bioactivities
- Type
- article
- Field-Weighted Citation Impact
- 0.00