Morphometric Analysis of Lateral Sulcus Asymmetry: Demographic Correlates and Neurosurgical Implications

This cadaveric study affirms the presence of consistent leftward LS asymmetry and highlights its modulation by sex, handedness, and age. By incorporating fixation correction and robust statistical methods, the findings reconcile anatomical and radiological data, offering valuable morphometric benchmarks for neurosurgical planning and future neuroimaging studies. These results should be interpreted as normative anatomical references rather than diagnostic criteria due to the inherent limitations of retrospective postmortem research.