Beyond the Inner Cell Mass: Evaluating the Impact of Inner Cell Mass Visibility on Implantation Prediction in Static Blastocyst Images – A Retrospective Cohort Study

Our findings suggest that the predictive accuracy of embryo outcomes does not significantly differ whether the ICM is clearly visible or not in the static 2D image. This supports the need to focus on other morphological and morphometric features that can be consistently evaluated. AI tools analysing these features may offer more reliable and objective clinical decision support.