Developing the Necessary Information for Sample Size Calculations in Future Spinal Cord Stimulation Clinical Trials

There is currently only low-quality evidence that spinal cord stimulation is effective for low back pain. This study supplies all the necessary information (effect estimates, variances and within-measure correlations across time) to better estimate sample sizes, a primary criticism of current evidence in this population. We also provide a preliminary indication as to which patient-reported outcomes and wearable measures are most effective in a spinal cord stimulation population.