Choledocholithiasis Following an Orthotopic Liver Transplant: A Case Report and Brief Review of the Literature

With advancements in transplant surgery, an orthotopic liver transplant remains the definitive treatment for end-stage liver disease. However, biliary complications, particularly strictures and choledocholithiasis, are among the most common causes of post-transplant morbidity and can significantly impact graft survival. Prompt recognition and timely intervention are essential to prevent progression to graft failure or the need for re-transplantation. We report a case of an orthotopic liver transplant patient who developed choledocholithiasis secondary to a duct-to-duct anastomotic biliary stricture. The patient was successfully managed with endoscopic retrograde cholangiopancreatography and biliary duct stent placement. This case highlights the importance of clinician awareness and the role of endoscopic therapy in the effective management of post-transplant biliary complications.

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Journal
Cureus
Published
2025-06-28
DOI
https://doi.org/10.7759/cureus.86915
Primary Topic
Gallbladder and Bile Duct Disorders
Type
article
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article

Choledocholithiasis Following an Orthotopic Liver Transplant: A Case Report and Brief Review of the Literature

Saraswathi Lakkasani, Eldia Delia, Gisha Mohan, Imran Khokhar et al.
Cureus
Gallbladder and Bile Duct Disorders
article

Choledocholithiasis Following an Orthotopic Liver Transplant: A Case Report and Brief Review of the Literature

Saraswathi Lakkasani, Eldia Delia, Gisha Mohan, Imran Khokhar, Anish Paudel
article en

Abstract

With advancements in transplant surgery, an orthotopic liver transplant remains the definitive treatment for end-stage liver disease. However, biliary complications, particularly strictures and choledocholithiasis, are among the most common causes of post-transplant morbidity and can significantly impact graft survival. Prompt recognition and timely intervention are essential to prevent progression to graft failure or the need for re-transplantation. We report a case of an orthotopic liver transplant patient who developed choledocholithiasis secondary to a duct-to-duct anastomotic biliary stricture. The patient was successfully managed with endoscopic retrograde cholangiopancreatography and biliary duct stent placement. This case highlights the importance of clinician awareness and the role of endoscopic therapy in the effective management of post-transplant biliary complications.

CureusVol. 17(6)
Suburban Community Hospital (US)
Good health and well-being
Openalex Percentile: Top 75%
Gallbladder and Bile Duct Disorders
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