Blunt Liver Injury: from Non-Operative Management to Transplantation. Systematic Review and Meta-Analysis. Part II: Secondary Control Points

Introduction. High incidence of blunt liver injuries, a large number of postoperative complications dictate the need to find optimal treatment options for patients’ management. The aim of the study was to conduct a systematic review of the literature and meta-analysis to compare various treatment options for patients with blunt liver injury. Methods. A systematic search for non-randomized studies was conducted from October 1, 2015, a systematic search for randomized studies were conducted without time restrictions, up to February 29, 2024. Results. There is a clear trend towards non-operative management of hemodynamically stable or stabilized patients, supplemented by angioembolization if necessary. Conclusion. More adequately-designed randomized clinical trials are needed to specify the treatment approach for patients with liver injuries.

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Journal
Journal of Experimental and Clinical Surgery
Published
2025-06-28
DOI
https://doi.org/10.18499/2070-478x-2025-18-2-131-160
Primary Topic
Abdominal Trauma and Injuries
Type
article
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article

Blunt Liver Injury: from Non-Operative Management to Transplantation. Systematic Review and Meta-Analysis. Part II: Secondary Control Points

D. S. Biriulev, V. V. Matyukhin, С. С. Маскин, S. M. Sigaev et al.
Journal of Experimental and Clinical Surgery
Abdominal Trauma and Injuries
article

Blunt Liver Injury: from Non-Operative Management to Transplantation. Systematic Review and Meta-Analysis. Part II: Secondary Control Points

D. S. Biriulev, V. V. Matyukhin, С. С. Маскин, S. M. Sigaev, Ashraf Rasheed, Vasily V. Alexandrov, Alexander Ya. Korovin
article en

Abstract

Introduction. High incidence of blunt liver injuries, a large number of postoperative complications dictate the need to find optimal treatment options for patients’ management. The aim of the study was to conduct a systematic review of the literature and meta-analysis to compare various treatment options for patients with blunt liver injury. Methods. A systematic search for non-randomized studies was conducted from October 1, 2015, a systematic search for randomized studies were conducted without time restrictions, up to February 29, 2024. Results. There is a clear trend towards non-operative management of hemodynamically stable or stabilized patients, supplemented by angioembolization if necessary. Conclusion. More adequately-designed randomized clinical trials are needed to specify the treatment approach for patients with liver injuries.

Journal of Experimental and Clinical SurgeryVol. 18(2)
Volgograd State Medical University (RU), Kuban State Medical University (RU)
Openalex Percentile: Top 74%
Abdominal Trauma and Injuries
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