Animal models of periodontitis – an integrative literature review

Sleep bruxism has been investigated among sleep-related movement disorders, highly prevalent in children with Attention Deficit Hyperactivity Disorder (ADHD). Children and adolescents with ADHD tend to have more sleep disorders compared to those with neurotypical development. Although there are still no specific guidelines for the treatment of bruxism in this population, it is believed that exogenous melatonin may contribute to improving sleep quality and reducing bruxism episodes. Therefore, the present study aimed to report the case of a 13-year-old male adolescent diagnosed with ADHD and frequent episodes of sleep bruxism. The patient had a history of talking and agitation during sleep, in addition to daytime fatigue. He reported grinding his teeth at least three times a week, in addition to fatigue in the facial muscles and tooth sensitivity when consuming cold foods. To improve sleep quality, it was decided to administer 3 mg of melatonin for a period of 60 days, together with sleep hygiene recommendations. A significant improvement in sleep quality and a reduction in bruxism-related symptoms were observed. Although this is a single case, the findings suggest that melatonin may represent a promising therapeutic alternative, reinforcing the need for larger and more controlled clinical studies to investigate its efficacy and safety in this population.

Authors

Publication Details

Journal
Journal of Orofacial Innovation and Science
Published
2025-06-27
DOI
https://doi.org/10.63281/jois.v2i1.30
Primary Topic
Natural Products and Biological Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Animal models of periodontitis – an integrative literature review

Bianca Lopes Cavalcante-Leão, L. Batista, Mariana Perotta, Francielle Topolski et al.
Journal of Orofacial Innovation and Science
Natural Products and Biological Research
article

Animal models of periodontitis – an integrative literature review

Bianca Lopes Cavalcante-Leão, L. Batista, Mariana Perotta, Francielle Topolski, Alfons Fischer
article en

Abstract

Sleep bruxism has been investigated among sleep-related movement disorders, highly prevalent in children with Attention Deficit Hyperactivity Disorder (ADHD). Children and adolescents with ADHD tend to have more sleep disorders compared to those with neurotypical development. Although there are still no specific guidelines for the treatment of bruxism in this population, it is believed that exogenous melatonin may contribute to improving sleep quality and reducing bruxism episodes. Therefore, the present study aimed to report the case of a 13-year-old male adolescent diagnosed with ADHD and frequent episodes of sleep bruxism. The patient had a history of talking and agitation during sleep, in addition to daytime fatigue. He reported grinding his teeth at least three times a week, in addition to fatigue in the facial muscles and tooth sensitivity when consuming cold foods. To improve sleep quality, it was decided to administer 3 mg of melatonin for a period of 60 days, together with sleep hygiene recommendations. A significant improvement in sleep quality and a reduction in bruxism-related symptoms were observed. Although this is a single case, the findings suggest that melatonin may represent a promising therapeutic alternative, reinforcing the need for larger and more controlled clinical studies to investigate its efficacy and safety in this population.

Journal of Orofacial Innovation and ScienceVol. 2(1)
Openalex Percentile: Top 74%
Natural Products and Biological Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Animal models of periodontitis – an integrative literature review — Bianca Lopes Cavalcante-Leão, L. Batista, et al. · Journal of Orofacial Innovation and Science (2025) | TGRS Research Map | TGRS