Insulin- and glucagon-producing cells in the liver and biliary–pancreatic axis of rats with experimentally induced metabolic syndrome

Our experiment of fructose-induced metabolic syndrome shows the appearance of Ins<sup>+</sup> and glucagon<sup>+</sup> ECs in extrahepatic biliary pathways and hepatocytes. Interestingly, SOX9<sup>+</sup> nuclei of LSECs are observed.

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Publication Details

Journal
Archives of Physiology and Biochemistry
Published
2025-06-28
DOI
https://doi.org/10.1080/13813455.2025.2503482
Primary Topic
Diet, Metabolism, and Disease
Type
article
Field-Weighted Citation Impact
0.00

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article

Insulin- and glucagon-producing cells in the liver and biliary–pancreatic axis of rats with experimentally induced metabolic syndrome

Ivaylo Stefanov, Maya Gulubova, A. Toleкova, Dimitar Chonov et al.
Archives of Physiology and Biochemistry
Diet, Metabolism, and Disease
article

Insulin- and glucagon-producing cells in the liver and biliary–pancreatic axis of rats with experimentally induced metabolic syndrome

Ivaylo Stefanov, Maya Gulubova, A. Toleкova, Dimitar Chonov, Dimitar Berbatov, N Aydoglu
article en

Abstract

Our experiment of fructose-induced metabolic syndrome shows the appearance of Ins<sup>+</sup> and glucagon<sup>+</sup> ECs in extrahepatic biliary pathways and hepatocytes. Interestingly, SOX9<sup>+</sup> nuclei of LSECs are observed.

Archives of Physiology and BiochemistryVol. 131(5)
Trakia University (BG), Inonu University (TR), Prof. Assen Zlatarov University (BG)
Trakia University
Zero hunger
Openalex Percentile: Top 78%
Diet, Metabolism, and Disease
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