The relationship between Vitamin D status and C-reactive Protein CRP with Coronavirus Disease (COVID-19) in Iraqi Older Patients

Vitamin D stimulates macrophages and epithelial and immune cell development of antimicrobial peptides, which may be significant in Bacterial or viral infection eradication. Case control study was carried out from 1/August 2020 till 15 /September 2020. A total of (100) subjects from (50±2) years old age and older were attending the Health centers of Baghdad City . The study includes 100 samples divided into 2 groups (or categories) : Fifty patients with coronavirus diseases (COVID-19) and Fifty apparently healthy subjects (as control). The mean(M) ±standard error of mean (SE) of vitamin D in (ng/ml) for corona virus patients was (14.57± 1.17), while for control group was (39.70 ± 2.23),a very highly significant difference (P<0.001) was found between patients and control groups. The finding of this study shown reduced in the mean level of vitamin D less than (30 ng/ml), the mean(M) ±standard error of mean (SE) of C-reactive protein (CRP) in (ng/ml) for corona virus patients was (1.98 ± 0.15), while for control group was (0.67 ± 0.04),a very highly significant difference (P<0.001) was found between patients and control groups. All (50) patient with corona virus shown elevated in level of serum C-reactive protein (CRP) level. Weak negative correlation (-0.189) with insignificant differences (P=0.224) were observed between vitamin D and C-reactive protein (CRP).