Canine Adrenomedullary and Pheochromocytoma Organoids: A Novel In Vitro Model
This study demonstrates the establishment of the first adrenomedullary and PCC organoid lines. While further optimization is needed, these organoids offer valuable potential as an in vitro model to investigate PCC pathophysiology and explore novel treatment strategies for this therapeutically challenging tumor.
Authors
- Marit F. van den Berg (ORCID: https://orcid.org/0000-0002-2016-119X)
- Monique E. van Wolferen
- Elpetra P.M. Timmermans‐Sprang (ORCID: https://orcid.org/0000-0002-3251-2014)
- Martijn H. J. R. van Faassen (ORCID: https://orcid.org/0000-0002-9142-6263)
- H.S. Kooistra (ORCID: https://orcid.org/0000-0002-8058-0492)
- Guy C. M. Grinwis (ORCID: https://orcid.org/0000-0002-1583-9648)
- Linda van den Berg (ORCID: https://orcid.org/0000-0001-5015-9106)
- Sara Galac (ORCID: https://orcid.org/0000-0001-9159-5596)
- Wilhelmina H. A. de Jong (ORCID: https://orcid.org/0000-0001-8392-6674)
- Fleur C Viets
- Fatima Danawar
Institutions
- University Medical Center Groningen (NL)
- University of Applied Sciences Utrecht (NL)
- Utrecht University (NL)
Publication Details
- Journal
- Endocrinology
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1210/endocr/bqaf114
- Citations
- 2
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78